Singlet oxygen generation by sonication using a water-soluble fullerene (C60) complex: a potential application for sonodynamic therapy
نویسندگان
چکیده
منابع مشابه
Photophysical Properties and Singlet Oxygen Generation Efficiencies of Water-Soluble Fullerene Nanoparticles
As various fullerene derivatives have been developed, it is necessary to explore their photophysical properties for potential use in photoelectronics and medicine. Here, we address the photophysical properties of newly synthesized water-soluble fullerene-based nanoparticles and polyhydroxylated fullerene as a representative water-soluble fullerene derivative. They show broad emission band arisi...
متن کاملSinglet oxygen generation by higher fullerene-based colloids
In this paper, the results of the synthesis and characterization of higher fullerene-based colloids is presented. The generation of singlet oxygen 1O2 (1Δg) by fullerene water-based colloids (nC60, nC70 and nC84) was investigated. It was found by electron paramagnetic resonance spectroscopy that the generation of singlet oxygen was the highest by the nC84 colloid. The amplitude of the electron ...
متن کاملWater-Soluble Fullerene (C60) Derivatives as Nonviral Gene-Delivery Vectors
A new class of water-soluble C60 transfecting agents has been prepared using Hirsch-Bingel chemistry and assessed for their ability to act as gene-delivery vectors in vitro. In an effort to elucidate the relationship between the hydrophobicity of the fullerene core, the hydrophilicity of the water-solubilizing groups, and the overall charge state of the C60 vectors in gene delivery and expressi...
متن کاملEfficient singlet oxygen generation from sugar pendant C60 derivatives for photodynamic therapy.
The amidation reaction between C60 with an activated ester group (1) and acetylated Glc (AcGlc) with an amino group (2) was performed to yield the target AcGlc-pendant C60 compound (3). The water soluble deacetylated compound, Glc-pendant C60 compound (4), exhibited high photocytotoxicity against HeLa cells due to the more efficient singlet oxygen generation as compared with that of Glc-pendant...
متن کاملCorrection: Efficient singlet oxygen generation from sugar pendant C60 derivatives for photodynamic therapy.
Correction for 'Efficient singlet oxygen generation from sugar pendant C60 derivatives for photodynamic therapy' by Shigenobu Yano et al., Chem. Commun., 2015, DOI: 10.1039/c5cc07353g.
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ژورنال
عنوان ژورنال: Polymer Journal
سال: 2020
ISSN: 0032-3896,1349-0540
DOI: 10.1038/s41428-020-0390-1